Clostridium septicum Empyema in an Immunocompetent Woman

A Case of Clostridium septicum Aortitis With Concomitant Adenocarcinoma of the Cecum

Clostridium septicum aortitis is a rare infection that is strongly associated with underlying adenocarcinoma of the colon. We report a case of a 73-year-old woman with peripheral vascular disease who presented after 4 weeks of severe abdominal pain. Abdominal computed tomography showed thickening of the cecal wall and gas in the aortic wall. Colonoscopy revealed a large ulcerated moderately dif...

Isolation of Clostridium septicum from cases of Malignant Oedema of Cattle in IRAN

Isolation and identification of Clostridium septicum from sheep-dung

  To study the existence of Clostridium septicum as probable agent associated with currently occurrence of black quarter in Urmia area, sheep-dung samples were collected. The bacteriological examinations on suspicious gram positive anaerobic spore-bearing bacilli which are in Clostridia genus include isolation and biochemical identification were performed. The results showed 28 different types ...

Molecular cloning of Clostridium septicum vaccine strain alpha toxin gene in E. coli

Clostridium septicum a Gram positive anaerobic bacterium produces several toxins including alpha, beta, gamma and delta. C. septicum alpha toxin is lethal and is responsible for a serious disease known as gas gangrene. The aim of the present study was to molecular cloning and sequencing of C. septicum vaccine strain alpha toxin gene. Genomic DNA was extracted using standard phenol and chlorofor...

Alpha Toxin Purification and Antibody Production Against Local Strain of Clostridium septicum NH2

BACKGROUND: Clostridium septicum has played a significant role as a causative agent of many acute fetal diseases in man and animals. Alpha- toxin is the main factor in the pathogenesis of C. septicum with hemolytic, necrotic and lethal activities. OBJECTIVES: The study was designed to evaluate alpha-toxin purification and antibody production rate against a local strain of C. septicum NH2 which ...